Karlstrom Lab Publications (linked to PDFs)

Guner B, Ozacar AT, Thomas JE, Karlstrom RO. (2008) Graded Hh and Fgf signaling independently regulate pituitary cell fates and help establish the PD and PI of the zebrafish adenohypophysis.Endocrinology. 2008 May 22. [Epub ahead of print]

Bergeron SA, Milla LA, Villegas R, Shen MC, Burgess SM, Allende ML, Karlstrom RO, Palma V. (2008) Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos. Genomics. 91(2):165-77

Guner B, Karlstrom RO. (2007) Cloning of zebrafish nkx6.2 and a comprehensive analysis of the conserved transcriptional response to Hedgehog/Gli signaling in the zebrafish neural tube. Mechanisms of Development Gene Expr Patterns. 2007 Apr;7(5):596-605

Cerda GA, Thomas JE, Allende ML, Karlstrom RO, Palma V (2006) Electroporation of DNA, RNA, and morpholinos into zebrafish embryos. Methods 39(3):207-11

Seth A, Culverwell J, Walkowicz M, Toro S, Rick JM, Neuhauss SC, Varga ZM, Karlstrom RO. (2006) belladonna/(Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain 4:725-35.

Barresi, M.J., Hutson, L. Chien, C-B., and Karlstrom, R.O. (2005) Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain. Development. 132(16):3643-56

Vanderlaan, G.M., Tyurina, O.V., Karlstrom, R.O., and Chandrasekhar, A., (2005) Gli Function is Essential for Motor Neuron Induction in Zebrafish. Developmental Biology


Feng, J., White, B., Tyurina, O., Guner, B. Larson, T, Lee, H.Y., Karlstrom, R.O., and Kohtz, J.D.  (2004) Synergistic and antagonistic roles of the Sonic hedgehog N- and C-terminal lipids. Development. 131, 4357-4370

Sbrogna, J.L., Barresi, M.J.F., and Karlstrom, R.O. (2003) Multiple roles for hedgehog signaling in zebrafish pituitary development. Developmental Biology. 254(1):19-35.

Karlstrom, R.O., Tyurina, O., Kawakami, A., Nishioka, N., Talbot, W.S., Sasaki, H., and Schier, A.F. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development. 130, 1549-1564

Ungos, J.M., Karlstrom, R.O. , and Raible, D.W. (2003) Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons. Development.  130: 5351-5362.

Sekimizu K, Nishioka N, Sasaki H, Takeda H, Karlstrom RO, Kawakami A. (2004) The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling. Development. 131(11):2521-32

Culverwell, J, and Karlstrom, R.O. (2002) Making the connection: Retinal axon guidance in the zebrafish. Sem. Cell and Developmental Biol. 13(6):497-506.

diIorio, P. J., J. B. Moss, J. L. Sbrogna, R. O. Karlstrom and L. G. Moss (2002). "Sonic hedgehog is required early in pancreatic islet development." Dev Biol 244(1): 75-84.

Kondoh, H., Ukhikawa, M., Yoda, H., Takeda, H., Furutani-Seiki, M., and Karlstrom, R.O. (2000) Zebrafish mutations in gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage. Mechanisms of Development 96: 165-174.

Karlstrom, R.O., Talbot, W.S. and Schier, A.F. (1999) Synteny cloning of zebrafish you-too: Mutations in the hedgehog target gli2 affect ventral forebrain patterning. Genes and Development 13, 388-393.

Karlstrom, R.O., Trowe, T. and Bonhoeffer, F. (1997) Genetic analysis of axon guidance in the zebrafish. Trends in Neurosciences 20, 3-8.

Karlstrom, R.O. and Kane, D.A. (1996) A time-lapse flip-book of zebrafish development. Development 123, 2-460.

Karlstrom, R.O., et al. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123, 427-438.

Trowe, T et al (1996)  Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio. Development 123, 439-450.


Brand M., et al (1996) Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123, 129-142.

Baier, H., et al (1996) Genetic dissection of the retinotectal projection. Development 123, 415-425.