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Karlstrom Lab: Developmental Neurobiology Using the Zebrafish as a Model System

The Karlstrom laboratory uses the zebrafish as a “simple” vertebrate system (its really not that simple) to study how the forebrain and pituitary gland form during embryogenesis, and to examine the signaling systems that control post-embryonic brain growth and neurogenesis. We focus on cell-cell signaling systems and have developed conditional gene regulation tools that allow us to manipulate Sonic Hedgeghog (Shh) signaling throughout the life cycle.

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