Spindle Formation
The dynamic rearrangements of microtubules as cells enter mitosis are shown in the following movie sequences of prophase and prometaphase LLC-Pk1 cells expressing GFP-tubulin. Notice that some interphase microtubules rapidly disassemble while others form bundles or clusters that are moved toward the forming spindle. For more information see: Rusan et al., Journal of Cell Biology 2002. 158:997-1003. Full-text available (PDF,474KB).
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Movie 1: Reeling them in #1 |
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Movie 2: Reeling them in #2 |
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Movie 3: U-turn |
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Movie 4: Zippering |
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Movie 5: Sliding |
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