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Microtubule Dynamic Instability

Microtubules display a non-equilibrium dynamic behavior termed dynamic instability in which individual microtubules stochastically switch between periods of growth and rapid shortening. In the following movies, the dynamic behavior of individual microtubules is observed in diverse cells.

Click on a thumbnail image to view the corresponding movie clip. (You will need QuickTime 7 to view these movies.)


Movie 1: Microtubules battle retrograde flow in a fish keratocyte
MicrotubuleInstability1

Movie 2: Dynamic Instability in an interphase LLC-Pk1 cell
MicrotubuleInstability2

Movie 3: Dynamic Instability in an interphase LLC-Pk1 cell
MicrotubuleInstability3










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Mitosis, Cytokinesis, & Cell Motility Laboratory
Pat Wadsworth - patw@bio.umass.edu
Biology Department - Univ. of Massachusetts Amherst
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