Research in Wadsworth lab
In the Wadsworth lab, we study cell division, the process by which one cell divides into two new daughter cells. During mitosis, a microtubule based structure -- the mitotic spindle -- assembles, aligns the duplicated chromosomes and segregates them into two daughter cells. Following chromosome segregation, the cytoplasm is divided during cytokinesis. You can view our movies of mitosis, cytokinesis, and cell motility by clicking on the subheadings on the left.
Mitotic Spindle in an LLC-Pk1 cell visualized with antibodies to tubulin (yellow); actin is visualized with phalloiden (blue).
Late anaphase LLCPk1 cell with microtubules visualized with antibodies to tubulin (green) and actin visualized with rhodamine phalloiden (red).