Using cutting edge microscopy to study high-speed cell migration

Project Description : 

Cells within your own body crawl over surfaces and through three-dimensional environments. Some cells crawl slowly, while others crawl very quickly. Conventional microscopy is good for imaging slow-moving cells on flat surfaces but cannot keep up with white blood cells like neutrophils that migrate a thousand times faster through 3D environments. To understand how high-speed cells interact with and crawl through complex environments, we use cutting edge lattice light sheet microscopy that has the necessary speed and resolution to image fast-moving cells and complex environments. (A video of the imaged cells can be viewed here We are also developing analytical tools to track the movements of cells, and how this motion changes their environments.

We are looking for a highly motivated student to help us analyze these data. The student will work closely with both Professor Fritz-Laylin and a data visualization specialist to apply new analysis methods to complex 3D microscopy data sets. Students MUST be available for at least 6 hours per week Monday-Friday between 9 a.m. and 5 p.m. in a minimum of 2-hour blocks. Active participation in group laboratory meetings and bi-weekly one-on-one meetings is required of all lab members. Qualities we are looking in applicants include: curiosity about the project (and cell biology in general), impeccable record keeping, excellent communication and interpersonal skills, and the ability to work both independently and collaboratively on a team. For more information about the lab see:

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Name of Lab: 

Fritz-Laylin Lab

Contact Person: 

Professor Lillian Fritz-Laylin

Contact E-mail:

Lab website: