Richard B. Arenas

Adjunct Professor Biology, University of Massachusetts
Chief of Surgical Oncology, Baystate Medical Center

R. Arenas PVLSI Web Site

M.D.: Robert Wood Johnson Medical School, New Brunswick, NJ
Residency: Hospital of Saint Raphael, New Haven, CT
UMDNJ - University Hospital, Newark, NJ
Fellowship: University of Chicago Chicago, IL

Breast, melanoma and gastrointestinal cancer. Sphincter preserving techniques for rectal cancer. Inflammatory bowel disease (Crohn's Disease and ulcerative colitis).

Representative publications:

Venkatasubramanian R, Arenas RB, Henson MA, Forbes NS. Mechanistic modeling of dynamic MRI data predicts that tumour heterogeneity decreases therapeutic response. Br J Cancer. 2010;103(4):486-497.

Shao R, Hamel K, Petersen L, Cao QJ, Arenas RB, Bigelow C, Bentley B, Yan W. YKL-40, a secreted glycoprotein, promotes tumor angiogenesis. Oncogene. 2009;28(50):4456-4468.

Ganai S, Arenas RB, Forbes NS. Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice. Br J Cancer. 2009;101(10):1683-1691.

Taylor, M.D., McClelland, M., Zanotti, S., Wolverton, D. and Arenas, R.B. The use of stereotactic core biopsy to clear the breast for conservation. (in preparation)

Arenas, R.B., McClelland, M., Fichera, A., Guo, Y., Michelassi, F. and Westbrook, C.A. Introduction of APC in vivo inhibits intestinal neoplasia in the Min mouse. ( Cancer Research , accepted with revisions)

Lew, J.I., Kim, R. McClelland, M., Laughlin, R., Romero, L., Fichera, A., Alverdy, J. and Arenas, R.B. Liposome-mediated gene transfer into the stomach, small bowel, and colon of mice using a single oral administration. ( Molecular Therapy , accepted with revisions)

Lew, J.I., Guo, Y., Kim, R., Vargish, L., Michelassi, M., and Arenas, R.B. Reduction of intestinal neoplasia by APC gene replacement and COX-2 inhibition is additive. Journal of Surgery of the Alimentary Tract 6 : 563-68, 2002.

Lew, J.I., Kim, R.K., Guo, Y., Michelassi, F., and Arenas, R.B. The inhibition of intestinal neoplasia with adenomatous polyposis coli gene therapy and cyclooxygenase-2 inhibitors. Surgical Forums LI , 2000.

Arenas, R.B., Fichera, A., Mhoon, D. and Michelassi, F. Total mesenteric excision in the surgical treatment of rectal cancer: a prospective study. Archives of Surgery 133 : 608-612, 1998.

Fichera, A., Michelassi, F. and Arenas, R.B. Selective Expression of liposomally delivered carcinoembryonic antigen promoter in human cancer cell lines. Diseases of the Colon and Rectum 41: 747-754, 1998.

Arenas, R.B ., Fichera, A., Mhoon, D., and Michelassi, F. Incidence and therapeutic implications of synchronous colonic pathology in colorectal adenocarcinoma. Surgery 122 : 706-710, 1997.

Arenas, R.B. , Fichera, A., Guo, Y. and Michelassi, F. Quantitation of in vivo gene delivery by restriction enzyme PCR generated polymorphism. Journal of Surgical Research 69 : 188-192, 1997.

• Arenas, R.B ., Fichera, A., Mok, P., Blanco, M.C. and Michelassi, F. Introduction of human adenomatous polyposis coli gene into Min mice via cationic liposomes. Surgery 120: 712-718, 1996.