Email:mmarkstein@bio.umass.edu
M. Markstein Biology Department Website

Ph.D.: University of Chicago
Postdoctoral Training: Harvard Medical School

Regulation of gene expression

We are interested in understanding fundamental mechanisms that coordinate and compartmentalize the transcription of genes as a function of their positions in the genome. We have found that the effects of genome position vary across cell types indicating that genome position effects are plastic. To study the mechanisms and consequences of genome plasticity we use the fruit fly Drosophila melanogaster where we develop transgenic probes, disease models, chemical assays and bioinformatics tools.

Representative publications: UMass ScholarWorks