Research in this group focuses on the molecular mechanisms driving biological processes from individual molecular folding to signaling pathways within cells. Emphasis is on the structural, chemical and physical properties of biomolecules, their assembly and their function in elaborate, interlocking networks.

Macromolecular Structure

Chambers, Chen, Garman, Gierasch, Hardy, Kaltashov, Knapp, Martin, Maroney, Thompson, Vachet, Vierling, Zimmermann

Molecular Basis of Disease

Chen, Garman, Gershenson, Gierasch, Hardy, Hebert, Heuck, Klingbeil, Knapp, Morita, Rotello, Thayumanavan, Vachet, Williams

Biomolecular Interactions

Bishop, Chambers, Chen, Garman, Gershenson, Gierasch, Griffith, Hardy, Hazen, Hebert, Heuck, M. Holden, Kaltashov, Kilfoil, Knapp, Martin, Muthukumar, Parkash, Ross, Rotello, Sandler, Schnell, Thayumanavan, Thompson, Weis, Vachet, Vierling, Zimmermann

Signal Transduction

Alfandari, Chase, Chen, Cheung, Fissore, Griffith, Gross, M. Holden, Normanly, Parkash, Schneyer, Thompson, Weis, Wu

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Cellular and Developmental Biology

Research in this group focuses on the molecular processes underlying cellular function and embryonic development, including how disease disrupts these processes. A variety of genetically tractable model systems are employed, including yeast, C. elegans, Drosophila, maize, Arabidopsis, Xenopus, zebrafish, and rodents. Research clusters include:

Cell Structure, Dynamics, and Function

Alfandari, Baskin, Bezanilla, Cannon, Cheung, Chen, Gross, Hazen, Hebert, Jensen, Kilfoil, Klingbeil, Lee, Li, Lopes, Ross, Schnell, Scordilis, Vierling, Wadsworth

Developmental Biology: Cell-Cell Signaling

Albertson, Alfandari, Barresi, Cheung, Griffith, Karlstrom, Li, Mager, Normanly, Osborne, Petersen, Poccia, Tremblay, Visconti, Wu

Cell Death

Forger, Jensen, Osborne, Petersen, Schwartz

Developmental Biology: Nervous System Development

Albertson, Alfandari, Barresi, Chase, Connor, Downes, Forger, Jensen, Karlstrom, Li, Petersen, Remage-Healey, Zoeller

Microbiology / Host-Microbe Interactions

Anguita, Baldwin, Black, Burand, Cannon, Clark, Chen, DeAngelis, Griffith, Leschine, Morita, Norkin, Pomposiello, Rich, Riley, Sandler, Williams

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Biomedicine

Researchers in this cluster use a variety of research tools and models, including in vitro cellular systems, primary cultures of tissues and stem cells, transplantation, genetically modified animals, and human specimens.

Reproduction

Bittman, Fissore, Mager, Petersen, Poccia, Visconti

Cancer and Apoptosis

Arcaro, Arenas, Forbes, Jerry, Norkin, Peyton, Rotello, Thayumanavan, Schneider, Shao , Xiao

Immunology

Anguita, Baldwin, Black, Osborne, Telfer

Neuroendocrinology

Bittman, Blaustein, De Vries, Forger, Karlstrom, Petersen, Remage-Healey, Zoeller

Environmental Toxicology

Arcaro, Clark, Parkash, Petersen, Zoeller

Stem Cells

Barresi, Fissore, Mager, Peyton, Telfer, Tremblay

Obesity and Diabetes

Kim, Park, Shetty, Schneyer























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