Improperly attached chromosomes

Maresca, T.J.

This spindle has a few problems because a number of chromosomes are attached to only one of the spindle poles. These types of attachments are dangerous because they will lead to mis-segregation of the genome during cell division.

Spinning disk confocal imaging of a live Drosophila S2 cell expressing GFP-tubulin (green) and an mCherry-tagged chromosomal protein (red).