This is a course for non-biology majors with two components, lecture and discussion section. We will explore biological principles at all levels of organization, from molecules, cells and organs to individuals, populations and the biosphere. Have you ever wondered…how basilisk lizards can literally run on water? …why we don’t yet have a vaccine against the HIV/AIDS virus? …why there is no rainforest in New England? …how bacteria help the Gulf ecosystem recover after the Deepwater Horizon oil spill? We will explore these and other questions to better understand how the living world works. Assessment includes evening exams, quizzes and written assignments. Gen Ed: BS.

Please click through to view descriptions of different instructors' versions of Biology 152

An introduction to the workings of the cell, focusing on themes of cellular structure, dynamics and energetics. This course is intended for students interested in a broad interdisciplinary approach to the biological sciences: frequent connections to chemistry, physics and mathematics will be made as the cell, its inner workings and malfunctions, are explored. In the laboratory, students will work in teams to conduct multi-week inquiry-based experiments in a laboratory 'core facility' to complement and expand on the lectures. This first semester course is prerequisite for the second semester in a full year introductory course sequence for life science majors. Gen Ed: BS.

We will investigate the process of biological evolution and the evolutionary history of life on Earth. Topics to be covered include natural selection, speciation (the formation of new species), and other causes of evolutionary change; the methods that evolutionary biologists use to investigate evolutionary processes and history; and an overview of life's history, focusing on major evolutionary innovations and transitions. Prerequisites: Grades of C or better in Biology 151, 152 & 153.

The basic objective of this laboratory is to introduce the methods and pleasures of genetic investigations, using a variety of organisms. It also reinforces Introductory Genetics (Biology 283). Topics include: Mendelian genetics, gene maps, variation in both DNA and in proteins, mutation induction and selection and DNA polymerase chain reaction. Prerequisite: BIOL 283 (may be concurrent).

A course in general ecology designed for undergraduate majors in biology. The course will cover the following topics: how the world works, its structure, history, and evolution; the Earth in space and extra-terrestrial influences; the energy budget and atmospheric circulation (weather); ecosystems and the flow of energy; biomes of the Earth; biogeochemical cycling; adaptations of plants and animals to their environments; population dynamics; interactions between organisms including the concepts of symbiosis and succession; human technology and ecological problems; and ideas for developing new relationships between human technology and ecological problems; and ideas for developing new relationships between humans and the natural systems we need for future survival. Prerequisite: Grades of C or better in Biology 151, 152 & 153.

Satisfies Junior Year Writing requirement for Biology majors. Students write and revise short papers on subjects likely to be encountered by biologists. Prerequisites: 3 biological science courses, for declared Biology majors only. Read more for Learning Goals and Instructor Narratives describing the focus of different sections.

A practical, hands-on approach to subjects within computational molecular biology. Recently, there have been huge advances in our ability to understand the genome and how different genomes interact in an environment using next-generation sequencing. Analyzing these revolutionary new datasets will be essential for molecular biology in the future. Foundational topics will include analysis of whole transcriptome, whole genome, and microbiome sequencing. No coding experience required.
Prerequisites: Open to Honors Students ONLY. C or better in BIOL 151 or 161H AND a C or better in BIOL 152 or 162H; BIOL 285 OR BIOCHEM 275 OR BIOL 283 (C or better)

This course functions as an introductory survey to neurobiology with a focus on cellular neuroscience. It provides a knowledge base for future advanced neuroscience courses and a stand-alone course for Biology majors. Topics within neuronal anatomy and physiology will be covered, including membrane potentials and neural transmission, sensory and motor systems, neuromodulatory and homeostatic systems. This course is not-for-credit for those who have previously taken Psych 330 or Biol 572

This project-based laboratory course will expose students to a range of techniques that are used by neurobiologists and physiologists, including electrophysiology, imaging, and molecular biology. Research projects and exercises will focus on the mechanisms that facilitate the development and physiological activities of the nervous and endocrine systems using model animal systems like zebrafish. We will also study human sensory physiology through non-invasive participatory lab exercises. Students may also have the opportunity to pursue projects examining tissue- and cell-physiology in non-neural tissues.

This fundamental ecology course emphasizes the quantitative skills needed to understand and conduct field research. The lectures introduce major ecological concepts, local vegetation types, and methods and techniques of gathering and analysing data. In laboratories, students collect original data at sites in the Connecticut Valley and write an original scientific paper. Prerequisite: an introductory biology course or consent of instructor.

This course introduces life in the sea from ecological and evolutionary perspectives. Topics will include primary and secondary production, interrelations of marine organisms and their environment (e.g. rocky intertidal, estuaries, interstitial communities, coral reefs, deep-sea communities), adaptations of marine organisms, human impacts on marine life, biodiversity, conservation, and aquaculture. Students will also learn about recent advances in marine research by reading primary literature on topics including reproduction, embryology, paleontology, metazoan body-plan evolution, evolution of development, and phylogeny.

Vertebrate collections are indispensable to the teaching of all whole organism biology courses. They are the repositories of Study of DNA, study skins, hides, preserved specimens, and comparative osteological material. Collections contain regional and global reference collections, provide secure storage for specimens of regional and historic importance, support a library of DNA samples and the specimens from which they were collected and also serve as the repository for type specimens. Maintenance of biological collections not only requires space and money but also require a highly dedicated and trained staff in order to be useful. Without constant maintenance even the smallest collections will deteriorate to the point of uselessness. Today many collections are being orphaned and/or discarded by colleges and universities. Qualified preparators, collections managers and curators are few and far between. During the course of this semester we will learn how to legally obtain, prepare, catalogue, and store new specimens and maintain an historic collection of vertebrate specimens. There will be one weekly lecture and at least 3 additional hours of lab per week. Lectures meet for 2.5 hrs. (6:00 ¬ 8:30 PM).

In this interdisciplinary course, we will explore the topic of imaging biological material, beginning with optics and basic microscopy. Students will perform hands-on exercises in the use of the light microscope, digital cameras, and image processing and quantification. Common pitfalls in imaging biological samples will be covered. Students will perform experiments to test and quantify various aspects of cell migration, cell cycle regulation, mitosis and endocytosis. Using the methods learned in the first portion of the class, students will design and complete a hypothesis-based experiment of their own design and present their findings. Bioimaging is a laboratory-based course. Enrollment is limited and requires permission of the instructor.

The goal of this laboratory course is to explore how researchers address modern biological questions through the use of model organisms. The course will be taught by a team of faculty whose own research employs these model systems to answer a diverse range of biological problems, including molecular evolution, plant development, yeast genetics, embryonic development and population genetics. Students will be introduced to several different model organisms that may include representative bacterial, plant, fungal, invertebrate, and vertebrate species. Lab exercises will employ sophisticated, state-of-the-art molecular methods and will tackle a variety of current biological questions.

Prerequisites: BIOLOGY 285 or BIOCHEM 275 or BIOLOGY 283, all with a grade of 'B' or better.

This 1-credit course fulfills one component of the General Education Integrative Experience requirement for Biology majors. The course is designed to help students appreciate what their academic training has been, and where it is leading them professionally. Students will learn about career options for life scientists and develop strategies and skills to position themselves to be successful. In order to satisfy the Integrative Experience requirement, BA-Biol and BS-Biol majors must also take one of the approved 3- or 4-credit Biology courses listed on their Academic Requirements Report.

This course covers current topics in genetics and and the social, ethical and legal issues surrounding genetic technology. Topics include genome structure and evolution, genetics of disease, personal genomics, human microbiomes and epidemiology. Students will have the opportunity to submit their DNA for genome-wide SNP and gut microbiome determination. Practical skills for analyzing genetic and genomic data are taught through weekly bioinformatic sessions in the R statistical programming language.

This course focuses on the processes affecting the distribution of genetic variation in populations of organisms, through space and time. The processes studied are the ones that operate during evolutionary change. Topics covered will include the Hardy-Weinberg principle, gene flow, genetic drift, recombination and linkage disequilibrium, natural selection, the effect of mating systems on diversity, and the neutral theory of evolution. Examples illustrating key concepts will be drawn from various kingdoms of life. The course will consist of lectures and occasional in class discussion. Prerequisites: Biology 280 or 283, plus Math 127 or 128 or Statistics 111 or 240 or ResEcon 211 or 212.

In this course we explore the cellular structure and function of human tissues and organ systems. The laboratory component offers a unique opportunity for you to develop and refine your skills in microscopy and visual identification of cells, tissues, and organs as well as tissue sectioning, staining, immunohistochemistry, and imaging. This includes a semester-long group project where you will prepare samples, section, stain, and analyze an organ of your choice and explore how the histology of this organ is altered by disease. This course provides a strong background for those interested in pursing a career in health sciences or graduate school in cell biology, morphology, or physiology.

An advanced course focused on the evolution of macromolecules and the reconstruction of evolutionary history of genes, proteins and organisms. Potential topics include databases and sequence matching, molecular phylogenetics, gene duplication and divergence, genome evolution, and horizontal gene transfer. The course will consist of lectures, computer demonstrations and class discussions. Text: Molecular Evolution, W.-H. Li, 1997 and readings from primary literature. 2 hour-exams and 1 term paper. Prerequisite: Biology 280 or equivalent course.

This is an introductory course designed to familiarize students with the diversity of fishes. We will provide an overview of the biology, evolution and ecology of fishes. A phylogenetic approach will be used to look at major primitive to advanced fish groups. No prior coursework is required to take this course, but students are expected to have a general biology background and be enthusiastic in learning about this diverse group of organisms. The textbook to be used is “The Diversity of Fishes” by Helfman, Collete and Facey 2004. Only selected portions of the text will be required during the course. The lab is designed to supplement the lecture course with hands-on dissection, anatomy of preserved specimens and dry skeletons and identification of major lineages. 1 essay exam, final, 2 lecture quizzes, 2 lab practicals.

Lectures and readings on comparative biology, phylogenetic relationships and evolution of mammalian groups. Lab involves a detailed introduction to the New England mammals and study of selected representatives of most mammalian orders, emphasizing systematics, function and morphology. 2 hour exams, 2 lab exams, and final. Prerequisite: any life science course beyond the introductory level.

This course will explore animal communication from several biological perspectives. We will explore how animals use different modalities of communication (sound, smell, electricity, etc.) and how these modes of sending and receiving information are limited by environmental constraints and their functions. We will look at the physiological and anatomical aspects of signal production and perception. The class will discuss the different types of messages encoded in signals and how they evolved. We will explore the evolution of sexually selected forms of communication (antlers, bird song, etc.) and the theories that attempt to explain their function and evolution. The lectures/discussions will draw on examples from a diverse selection of animals (insects, fish, birds, and mammals). Students will also work on projects where they will learn how to analyze and interpret different forms of vocal and visual communication.

Physiological principles governing the function of major organ systems (nervous, circulatory, respiratory, endocrine) and their interactions in vertebrates emphasizing mammals especially humans. Lab exercises designed to illustrate physiological principles using modern approaches. Prerequisite: Biology 285 or equivalent and at least one semester of Organic Chemistry.

The role of hormones in growth, metabolism and reproduction, molecular mechanisms of hormone action, and feedback control of hormone secretion. 2 hour-exams, final, and 1 class presentation. Prerequisite: Biology 288 or consent of instructor.

Biology of nerve cells and cellular interactions in nervous systems. Lectures integrate structural, functional, developmental, and molecular approaches. Topics include neuronal anatomy and physiology, membrane potentials, synapses, development of neuronal connections, visual system, control of movement, and neural plasticity. Text and reserve readings, 2 hour-exams, final, short critique paper. Prerequisite: Biology 285 or 523; or both Psychology 330 and Biology 152.

How do complex morphologies develop from a single-cell embryo? What makes the human hand different from the horse's hoof, the bat's wing, or the flipper of a whale? These and related questions will be addressed as we explore the genetic and developmental basis of evolutionary change.

This course will provide an on-site introduction to the world's epicenter for aquatic and terrestrial diversity, the Amazon Basin. We will examine the Amazon's fauna, flora and ecosystems and we will have a chance to interact with people in small villages. Via riverboat, we'll travel to Careiro Island on the Amazon river, and to Novo Airao in the Negro River. Most of the time will be sent canoeing on floodplains and forests, the best way to experience the diversity of animals and plants. Students will complete self-designed research projects comparing the biodiversity of different habitats of the black and white water river systems.

This course will introduce the human microbiome and show how an understanding of the dynamics and function of the indigenous microbiota has altered our view of microbes in maintaining homeostasis and causing disease. It will discuss how disruption of the beneficial functions of the microbiota can lead to disease. Methods for studying the microbiota will be introduced as part of a conceptual framework for using these methods to delineate novel roles for microbes in health. Key associations between specific changes in the microbiome and disease will be discussed. This will lead to an explanation of how the intentional manipulation of the microbiota, either by restoring missing functions or eliminating harmful functions, may lead to novel methods to prevent or treat a variety of diseases. With the explosion of studies relating the microbiome to health and disease, this course aims to provide a foundation for students to follow this developing area of biomedical research.

There are a mind-boggling 400,000 species of plants on earth, with new species discovered every year. Plants have evolved over hundreds of millions of years to efficiently capture the sun's energy and cycle oxygen in the atmosphere. How did this diversity come to be, and why are plants so varied in form and function? Explore the plants of the world in a hands-on laboratory setting using live temperate and tropical plants from the UMass greenhouses and forests. You will use this new-found knowledge to study your favorite plant in an independent project for the web.