First semester of a full year course for science majors. Introduction to biochemical basis of living systems, cell and molecular biology, mitosis and meiosis, principles of genetics, developmental biology. Includes lecture and discussion sections.. Gen Ed: BS.

This course is a 2 credit laboratory experience that allows students to apply the biological concepts covered in Biology 151 and 152 Introductory Biology in laboratory and field settings. Students will develop and practice scientific research skills while exploring the areas of genetics, cell and molecular biology, evolution, and ecology. To enroll, students must be co-enrolled in Biology 152 (Introductory Biology II) or have completed the 2 semester Introductory Biology Sequence (Biology 151 and 152).

A lecture series introducing the natural history, reproductive biology, functional morphology, and evolution of the major groups of marine vertebrates. Species native to the North Atlantic and Caribbean will be emphasized, including selected sharks, teleosts, turtles, birds and mammals. Grading will be based on two multiple choice exams. A note set must be purchased (at cost), but no other text is required. Prerequisites: Grades of C or better in Biology 151, 152 & 153.

Introduction to genetics including Mendelian and molecular developmental. Examples from a wide variety of organisms. Satisfies major requirements in Biology.

Course designed for sophomore-level majors in life sciences. Building upon concepts introduced in BIOL 100/101, consideration is given to structure and function at the cellular, subcellular, and molecular levels. The course is equally divided between aspects of molecular and cellular biology. Prerequisites: a grade of C or better in Biology 151, 152 & 153 and in Chemistry 111 & 112.

Lectures cover the physiology of humans and other vertebrates on a system by system basis (e.g. circulatory system, respiratory system, digestive system, etc.). Emphasis is placed on understanding fundamental physiological concepts such as diffusion, membrane potentials, biomechanics and biocontrol. Problem sets and exams give students practice working with physiological concepts. This course concentrates primarily on human physiology, but examples from other vertebrate animals are used to illustrate some physiological phenomena. Prerequisites: Grades of C or better in Biology 151, 152, & 153.

We have two goals in this course. The first, and most important, is to introduce undergraduate Biology students to some of the many fascinating aspects of Plant Biology, especially as these differ from animal biology. For instance, did you know that plants are moving (on a large scale) all the time? It’s the truth, but in a very different time scale than we animals use. How do plants do that without the benefit of muscles and skeleton? Have you ever thought about how, in the absence of a pumping heart, plants’ circulatory systems work? After all, the water at the top of a tree got there from roots in the ground, but no pump was involved. Plants don’t have an immune system, and yet, they ‘stand and fight’—literally rooted to the spot—taking on all types of pathogens, as well insects and other predators. What strategies do plants use to overcome these attacks? Have you ever wondered about how biotechnology is used in agriculture? We have all heard news stories about GMO’s (genetically modified organisms). What are these and what makes them useful or dangerous? These are the types of topics we will be covering in this course. The second goal for this course is to provide a convenient way for UMass Biology majors to accomplish their plant biology course requirement. The course is open to any student who has successfully (with a C or better) completed the Introductory Biology series Biol 151, 152 & 153.

In this class we will discuss concepts and applications of modern DNA technology including an introduction to the basic concepts pertaining to the emerging field of genomics. We will begin by describing key molecular methods (cloning, sequencing, blotting, PCR) and how they are used in gene analysis. We will then move on to consider how entire genomes are analyzed, and will familiarize ourselves with some of the basic bioinformatics' tools that are commonly used by working biologists. Finally we will consider the methods used to manipulate genomes as a means to determining gene function. This course is intended for sophomores and juniors, and should serve as a bridge between 200-level courses and more advanced, specialty courses (e.g., 500-level courses). Prerequisite: Biology 285 or Biochem 275.

Cellular and Molecular Biology Lab is a hands-on project-based course where students explore aspects of cell biology, particularly how proteins within cells are targeted to their correct intracellular location. The class will focus on targeting proteins to intracellular organelles. To approach this cell biological question, students will be using a host of current tools in the life sciences including, bioinformatics, DNA cloning, cell transformation, and microscopy. This course is meant to provide a laboratory perspective to many of the concepts taught in Biology 285. It is NOT necessary to have taken Biology 285, but students must at least be enrolled in Biology 285 concurrently with this course.

Most courses present the prevailing wisdom of the field as artistically rendered figures that summarize a large body of information and present it as dogma. However, that’s not how the field actually advances. Breakthroughs occur when researchers publish original research papers in peer-reviewed journals. Sometime the importance of the work is obvious at the time of publication and sometimes it takes many years for the true significance of the work to be appreciated. The “Great Papers in Biology” course is designed to allow students to read seminal papers in biology with the goals of: 1) understanding, in detail, how the experiments were conducted; 2) how the results were interpreted; and 3) how the work changed scientists understanding of biology. Papers to be discussed will represent a wide range of fields within Biology, including: developmental biology, genetics/genomics, neuroscience, cell biology, and the mechanisms of disease.

This three-credit will be limited to 20 upper division students who will be expected to read and discuss each of the papers. Students will be evaluated on the basis of their presentation and on class participation.

Introduction to experimental methods in ecology with an emphasis on rigorous experimental design, hypothesis testing, methods of data collection, and introductory data analysis. Laboratory will involve field trips, greenhouse experiments, and computer time.

Vertebrate collections are indispensable to the teaching of all whole organism biology courses. They are the repositories of Study of DNA, study skins, hides, preserved specimens, and comparative osteological material. Collections contain regional and global reference collections, provide secure storage for specimens of regional and historic importance, support a library of DNA samples and the specimens from which they were collected and also serve as the repository for type specimens. Maintenance of biological collections not only requires space and money but also require a highly dedicated and trained staff in order to be useful. Without constant maintenance even the smallest collections will deteriorate to the point of uselessness. Today many collections are being orphaned and/or discarded by colleges and universities. Qualified preparators, collections managers and curators are few and far between. During the course of this semester we will learn how to legally obtain, prepare, catalogue, and store new specimens and maintain an historic collection of vertebrate specimens. There will be one weekly lecture and at least 3 additional hours of lab per week. Lectures meet for 2.5 hrs. (6:00 ¬ 8:30 PM).

In this interdisciplinary course, we will explore the topic of imaging biological material, beginning with optics and basic microscopy. Students will perform hands-on exercises in the use of the light microscope, digital cameras, and image processing and quantification. Common pitfalls in imaging biological samples will be covered. Students will perform experiments to test and quantify various aspects of cell migration, cell cycle regulation, mitosis and endocytosis. Using the methods learned in the first portion of the class, students will design and complete a hypothesis-based experiment of their own design and present their findings. Bioimaging is a laboratory-based course. Enrollment is limited and requires permission of the instructor.

The goal of this laboratory course is to explore how researchers address modern biological questions through the use of model organisms. The course will be taught by a team of faculty whose own research employs these model systems to answer a diverse range of biological problems, including molecular evolution, plant development, yeast genetics, embryonic development and population genetics. Students will be introduced to several different model organisms that may include representative bacterial, plant, fungal, invertebrate, and vertebrate species. Lab exercises will employ sophisticated, state-of-the-art molecular methods and will tackle a variety of current biological questions.

Prerequisites: BIOLOGY 285 or BIOCHEM 275 or BIOLOGY 283, all with a grade of 'B' or better.

This 1-credit course fulfills one component of the General Education Integrative Experience requirement for Biology majors. The course is designed to help students appreciate what their academic training has been, and where it is leading them professionally. Students will learn about career options for life scientists and develop strategies and skills to position themselves to be successful. In order to satisfy the Integrative Experience requirement, BA-Biol and BS-Biol majors must also take one of the approved 3- or 4-credit Biology courses listed on their Academic Requirements Report.

This course covers current topics in genetics and and the social, ethical and legal issues surrounding genetic technology. Topics include genome structure and evolution, genetics of disease, personal genomics, human microbiomes and epidemiology. Students will have the opportunity to submit their DNA for genome-wide SNP and gut microbiome determination. Practical skills for analyzing genetic and genomic data are taught through weekly bioinformatic sessions in the R statistical programming language.

Structure and function of components of the plant cell, including the wall, membranes, vacuoles, the cytoskeleton and various organelles. Aspects of development at the molecular, tissue and whole plant level. Current theories pertaining to how plants react to hormones, light and daylength. Responses to stresses such as drought, temperature and touch, and the nature of plant defenses against predation and disease. Prerequisite: Biology 151, 152 & 153.

Detailed approach to the structure and evolutionary relationships of vertebrates. Lecture: evolutionary and functional significance of structures in different groups. Lab: evolutionary trends and specializations, experience in dissection. 2 hour exams, final; 2 lab exams. Prerequisite: Grades of C or better in Biology 151, 152 & 153.

An advanced course for students who have already taken an introductory course in evolution and who are willing to make an active contribution to classroom discourse. We will discuss both evolutionary mechanisms and evolutionary history. Potential topics include evolutionary genetics, the role of chance in evolution, speciation and species concepts, the origin of life, the tempo of evolution, extinction, the evolution of behavior, evolutionary history of selected groups, research methods in evolution. Prerequisite: Biology 280 or equivalent course.

The course provides an overview of the systematics, anatomy, and evolution of all the major, living lineages of amphibians and reptiles, with an emphasis on the herpetofauna of Eastern North America and New England. The laboratory is organized around three approaches: anatomical studies; studies of live organisms; and studies of regional and global amphibian and reptile diversity. If weather permits, there will be one field trip near the end of the semester. Some dissection is required. Prerequisite: Biology 521 or permission of the instructor.

Lecture: origin of birds, speciation, diversity, flight, territoriality, migration, navigation, communication, conservation. Lab: bird identification, anatomy, field studies. Text and field guide required. Lab practicals, 2 lecture exams plus final. Prerequisite: upper level biology course or consent of instructor.

Animals have evolved a remarkable diversity of behavioral patterns, used in a wide range of ecological and social contexts. Our first goal in this course will be to examine the mechanisms responsible for the expression of behavior: for example, how do birds locate prey; how do crayfish avoid becoming prey; and how to crickets and birds develop species-specific communication signals? To help answer these questions we will make use of neurobiological, hormonal, genetic, and developmental perspectives. Our next goal in the course will be to examine the evolutionary bases of behavior, asking for example why animals move, forage, hide, communicate, and socialize as they do. To address these questions we make use of optimality theory and other behavioral ecological perspectives. Other topics in the course will include sexual selection, human behavior, and the role of behavior in establishing biodiversity. Prerequisite: introductory biology or psychology course; or consent of instructor and at least sophomore level standing.

Discussion of cell structure and function; emphasis will be placed on the properties of individual molecules that contribute to cell function. Topics will include the mechanism and regulation of cell division; interactions of cells with each other and with the extracellular environment; cell motility; and the organization of membrane systems. Techniques used to study cells will also be discussed. Format will include both lectures and class presentations; quizzes, mid-term exams and written assignments will be included. Prerequisite: Biology 285.

Lectures cover the physiology of vertebrates and invertebrates on a system by system basis (e.g. circulatory system, digestive system, etc.). Comparisons between animals within each system and adaptations to "extreme" environments are emphasized. Weekly problem sets provide practice in physiological reasoning for each system covered. Animal design projects involve modeling the physiological systems of an extinct animal. Prerequisite: a grade of C or better in Biology 151, 152 & 153.

The mechanisms which generate endogenous daily, tidal, and annual oscillations in organisms will be considered at the level of physiology, genetics, and molecular and cell biology. The synchronization of these rhythms by the physical environment and the use of the clock for photoperiodism, reproductive cycles and migratory orientation will be studied. Readings from original scientific literature will be assigned. For junior and senior life science majors and graduate students. Prerequisite: BIOL 285 or equivalent.

Analysis of organismal development, with special attention to cell-cell interactions, cells fate determination, gene regulation, signal transduction, pattern formation and terminal differentiation. The emphasis will be on molecular approaches to these problems. Prerequisites: Biology 285 or equivalent recommended.

This course covers current techniques in genetics and genomics and the social, ethical and legal issues surrounding genetic technology. Topics will include, but are not limited to DNA sequencing technology, genome structure and evolution, genetics of disease, personal genomics, and the human microbiome. Practical skills for analyzing genomic data are taught through a weekly computational genomics session. Prerequisite: Biology 283 with grade of C or higher.

This course deals with evolutionary processes on molecular and genetic levels. Topics include the use of genomic data to detect natural selection, the evolution of genome size and structure, speciation, the evolution of sex, and genomic conflict. The course consists of computer-based bioinformatics lab sessions (including an introduction to Python) which provide training in analytical methods related to detecting genetic variation, phylogenetics and comparative genomics alternating with discussions of papers from the scientific literature.