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Hedgehog Signaling and Neural Stem Cells

The Karlstrom Lab investigates the formation and growth of the ventral forebrain and pituitary gland in the zebrafish. We are now investigating how cell-cell signaling mediated by a small protein called “Hedgehog” (Hh) controls stem cell proliferation to regulate tissue growth and cell renewal in larvae and adults. This position is for students wishing to pursue serious honors thesis research, including summer research. The student will work to characterize zebrafish transgenic lines that allow the conditional (time and tissue specific) regulation of Hh signaling in zebrafish.

Zebrafish Husbandry and Transgenics LInes

The Karlstrom Lab investigates the formation and growth of the ventral forebrain and pituitary gland in the zebrafish. We have created several transgenic lines that allow us to study how cell-cell signaling systems control pituitary and forebrain formation in the embryo. We are now investigating how these same signaling systems control stem cell proliferation to regulate tissue growth and cell renewal in larvae and adults. This entry-level undergraduate project is to work with our fish facility manager to maintain these important zebrafish lines.

Mycological and molecular approaches to turf pathology research.

The turf pathology lab is looking for motivated independent study students interested in plant pathology to work on projects involving mycology and microbiology of the turf grass pathogen Sclerotinia homoeocarpa. This particular turfgrass pathogen has developed resistance to multiple fungicide classes and we have established a large collection of isolates from resistance screening for golf courses. The Jung lab researches topics such as fungicide resistance detection, heterokaryosis, molecular mechanisms of fungicide resistance and nematology.

3D reconstruction of American alligator cloacal anatomy

The Kelly lab studies reproductive anatomy in vertebrates: one ongoing project in the lab is describing changes in phallus anatomy within the Archosauria and determining how those changes affected erectile function within this lineage. We recently prepared a pair of American alligator cloacae in thick serial sections, and I am looking for a motivated student to help analyze their anatomical components and develop a three dimensional virtual model of the structure.

Anti-parasitic effects of plant compounds in bumblebee diets

Bumblebees are important pollinators of both agricultural and wild plants, but populations of some North American species are declining, in part due to parasites. I am looking for a student to assist with experiments examining the effects of bumblebee diets on the severity of parasitic infections. Many human medicines are derived from plants. I study the different chemicals that bees consume in nectar and pollen to determine the antimicrobial properties of individual compounds and mixtures.

The Evolution of burrowing system

Fossoriality, a life dedicated to living underground, has evolved several times in mammals. However, we know very little about burrowing, in large part because animals burrow in opaque substrates (soil and sand). In the Dumont lab, we study burrowing on moles. Moles are highly specialized diggers with specialized forelimb morphologies, including robust humeri, elongated scapulae and enlarged hands with six digits. In this project, we investigate how these derived morphologies increase the efficiency of burrowing in three North American moles.

The Effects of Sleep on Memory Consolidation across the Lifespan

The Cognition and Action Lab is seeking research assistants to help with a variety of projects designed to investigate the relationship between sleep and memory consolidation in young and older adults. The neural basis of this relationship will also be assessed. Primary activities will include administering memory tests, applying electrodes to record sleep activity (polysomnography recordings), and attending weekly lab meetings. Must have a GPA of at least 3.25. Please respond as soon as possible if you are interested!

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