Cell and Molecular Biology of Yeast Mitosis

You will learn to use a combination of genetics, biochemistry, cell biological assays, and fluorescence microscopy to try to understand the process of mitotic spindle stabilization and/or microtubule dynamics and/or dynein motor regulation. The project depends on your specific experience and interest. For example, it could involve analyzing movies of yeast cells labeled with GFP-tubulin, or constructing a brand new plasmid for gene tagging, or performing western blotting to confirm protein levels, or using the fluorescence microscopy to capture dynamic spindle behavior.

Genetics and molecular mechanisms of host-microbe mutualism

The Wang Lab, located in the Life Science Laboratories, is interested in the mechanisms of beneficial host-microbe interactions. Our experimental system is the symbiosis between legumes and nitrogen-fixing rhizobia, with important economic and environmental relevance, as well as similarities to pathogenic interactions. The BURA student will be engaged in dissecting the genetic basis of the nitrogen-fixing symbiosis, in particular characterizing the defects in host mutants unable to sustain a successful symbiotic relationship.

Feeding Behavior of Stable Flies

Join a research group that is interested in better understanding the physiology of stable flies, blow flies, house flies and Drosophila. Currently we are investigating various aspects of feeding behavior as it relates to a special organ known as the crop. This organ is essential in controlling short term and long term feeding, as well as helping regulate the fly’s blood sugar levels. Because of this, this organ is especially important in current studies related to human diabetes.

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