Kunkel Lab Publications

Submitted or in press

  • Accepted MS C Dedic; TS Hung; AM Shipley; A Maeda; T Gardella; AL Miller; P Divieti Pajevic; JG Kunkel; A Rubinacci. Calcium fluxes at the bone/plasma interface: acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes. {accepted by Bone July 24, 2018}.
  • Jacky Hung, Sarah Webb, Carla Palumbo, Agnieszka Lesniak, Alan Shipley, Alessandro Rubinacci, Joseph Kunkel, and Andrew Miller. (2018). "Zebrafish scales play a role in the short-term homeostatic regulation of ECF Ca2+ levels". Journal of General Physiology. {submitted}


    1. Hepler PK, Kunkel JG, Rounds CM, Winship LJ (2012) Calcium entry into pollen tubes. Trends Plant Sci 17:32-38
    2. PDF Kunkel JG, W Nagel and MJ Jercinovic. (2012) Mineral Fine Structure of the American Lobster Cuticle. Journal of Shellfish Research 31(2): 515-526.
    3. Preprint PDF Kunkel JG and MJ Jercinovic. (2013) Carbonate apatite formulation in cuticle structure adds resistance to microbial attack for American lobster. Marine Biology Research 9(1): 27-34.
    4. Preprint PDF Kunkel JG. (2013) Modeling the Calcium and Phosphate Mineralization of American Lobster Cuticle. Can. J. Fish. Aquat. Sci. 70(11): 1601-1611. Journal Link D
    5. PDF Isaac Zepeda, Rosana Sanchez-Lopez, Joseph G. Kunkel, Luis A. Banuelos, Alejandra Hernandez-Barrera, Federico Sanchez, Carmen Quinto and Luis Cardenas. (2014) Visualization of highly dynamic F-actin plus ends in growing Phaseolus vulgaris root hair cells and their responses to Rhizobium etli Nod factors. Plant and Cell Physiology 55(3): 579-591.
    6. PDF Jennie Warrell in lab of Joe Kunkel. (2014) Landmark Analysis of Dragonfly Hindwings: A 2dimensional model for morphological evolution. Poster in 15th Annual Student Research and Scholarship Symposium, UNE May 2 2014.
    7. Poster Abstract Joseph G. Kunkel. (2014) An Acidic Bottom Feature associated with Wilkinson's Basin in the Gulf of Maine. RARGOM Meeting, Boston University, Sept 30, 2014.
    8. Meeting Abstract Miller AL, JT Hung, A Rubinacci, JG Kunkel, AM Shipley, PD Pajevic, CH Angus, SE Webb. (2014). The Zebrafish Scale: A Model for studying the molecular regulation of Mammalian Bone/Plasma Ca2+ Exchange, The Immediate Bone Wounding Response, and Bone Regeneration and Repair. CSH Asia Conference, 2014 Bone & Cartilage: from Development to Human Diseases, Suzhou, China, November 3-7, 2014
    9. PDF Kunkel JG. (2015). My Adventure Volunteering on NOAA Ships. Fisheries 40(8):360-361.
    10. PDF Kunkel JG, M Rosa, AN Bahadur. (2015). Toward a modern interpretation of the American lobster shell using X-ray tomography. The Lobster Newsletter 28(2):19-21.
    11. PDF Poster Kari L Lavalli, Joseph G Kunkel & Ehud Spanier. (2016). The Mediterranean Slipper Lobster, Scyllarides latus, Uses Apatite and Fluor-Apatite to Protect its Sensory Organules. Benthic Ecology. Mar 16-18, 2016. Portland ME.
    12. PDF Kunkel JG, M Rosa, AN Bahadur. (2016). 3D-Xray-tomography of American lobster shell-structure. An overview. Fisheries Research 186(1): 372-382.
    13. Kunkel, Joseph G (2017). Combining Lobster Shell Bouligand Spiral with Basal Granule STL files to display a combined structure using an R script. Mendeley Data, v1 Data Set.
    14. Kunkel Joseph G, Melissa Rosa, Brian Tarbox, Sabine Hild, Michael J. Jercinovic, Ali N. Bahadur (2018). Recognizing Incipient Epizootic Shell Disease Lesions in the Carapace of the American Lobster, Homarus americanus, H. Milne Edwards 1837. Bull Mar Sci 94(3):863-886..
    15. Kunkel Joseph G, Melissa Rosa, Brian Tarbox, Sabine Hild, Michael J. Jercinovic, Ali N. Bahadur (2018). Recognizing Incipient Epizootic Shell Disease Lesions in the Carapace of the American Lobster, Homarus americanus, H. Milne Edwards 1837. Bull Mar Sci 94(3)Suppl. Info..
    16. JG Kunkel, B Tarbox, S Hild, AN Bahadur, MJ Jercinovic. (2018). An Apatite for American Lobster. Poster. Conference Abstract. Goldschmidt Boston 2018.
    17. Joe Kunkel's Lobster Shell Disease Training Website. (2018). Organized in conjunction with NOAA NMFS and Maine DMR.


    1. PDF Cardenas L, TL Holdaway-Clarke, F Sanchez, C Quinto, JA Feijo, JG Kunkel and PK Hepler. (2000). Ion changes in legume root hairs responding to Nod factors. Plant Physiol 123, 443-52.
    2. PDF Faszewski EE and JG Kunkel. (2001). Covariance of ion flux measurements allows new interpretation of Xenopus laevis oocyte physiology. J Exp Zool 290, 652-61.
    3. PDF Feijo JA, J Sainhas, T Holdaway-Clarke, MS Cordeiro, JG Kunkel and PK Hepler. (2001). Cellular oscillations and the regulation of growth: the pollen tube paradigm. Bioessays 23, 86-94.
    4. HTML Kunkel, JG (2001). Project- and Group-Based Learning of Junior Writing in Biology. In PATHWAYS TO CHANGE. eds. C. D'Avanzo and R. Yuretich. Journal of Mathematics and Science: Collaborative Explorations 4: 25-42.
    5. PDF Kunkel JG, L-Y Lin, Y Xu, AMM Prado, JA Feijo, PP Hwang and PK Hepler. (2001). The strategic use of Good buffers to measure proton gradients about growing pollen tubes. In Cell Biology of Plant and Fungal Tip Growth (A Geitman, Ed.), pp. 14pp. IOS Press, Amsterdam.
    6. PDF Straatman KR, SK Dove, T Holdaway-Clarke, PK Hepler, JG Kunkel and VE Franklin-Tong. (2001) Calcium signalling in pollen of Papaver rhoeas undergoing the self-incompatibility (SI) response. Sexual Plant Reproduction 14: 105-110.
    7. PDF Franklin-Tong VE, TL Holdaway-Clarke, KR Straatman, JG Kunkel and PK Hepler. (2002). Involvement of extracellular calcium influx in the self-incompatibility response of Papaver rhoeas. Plant J 29: 333-345.
    8. PDF Holdaway-Clarke TL, NM Weddle, S Kim, A Robi, C Parris, JG Kunkel and PK Hepler.  (2003)   Effect of extracellular calcium, pH and borate on growth oscillations in Lilium formosanum pollen tubes.  J. Exp. Bot. 54: 65-72.
    9. PDF poster Christensen, A and JG Kunkel. (2003)  Calmodulin During Early Zebrafish Development. ASCB Meeting, SF Moscone Center, Dec 10-14, 2003. Abstract.
    10. PDF Zydlewski J, SD McCormick and JG Kunkel (2003) Late migration and seawater entry is physiologically disadvantageous for American shad juveniles. Journal of Fish Biology 63: 1521-1537.
    11. PDF Kunkel JG, MJ Jercinovic, DA Callaham, R Smolowitz, M Tlusty. (2005)  Electron Microprobe Measurement of Mineralization of American lobster, Homarus americanus, Cuticle: Proof of concept. 2005 Lobster Shell Disease Workshop, UMass Boston. New England Aquarium. Aquatic Forum Series, pages 76-82.
    12. PDF abs Kunkel JG, R Smolowitz, MJ Jercinovic, M Tlusty. (2005) Shell Disease in the American Lobster, Homarus americanus, Involves Disolution of a Calcium Apatite Cuticular Layer. ASCB Meeting, SF Moscone Center, Dec 10-14, 2005. Abstract L356. Poster JPEG.
    13. PDF Marenzana M, AM Shipley, P Squitiero, JG Kunkel, A Rubinacci. (2005) Bone as an ion exchange organ: evidence for instantaneous cell-dependent calcium efflux from bone not due to resorption. Bone 37:545-554.
    14. Pre-print Kunkel JG, S Cordeiro, Y(J) Xu, AM Shipley and JA Feijo. (2005) The use of non-invasive ion-selective microelectrode techniques for the study of plant development. Chapter V in Plant Electrophysiology- Theory and Methods ed. by AG Volkov, Springer-Verlag, Berlin/Heidelberg, pp 109-137.
    15. PDF Lin L-Y, J-L Horng, JG Kunkel and P-P Hwang. (2006) Proton pump-rich cell is secreting acid in skin of zebrafish larvae (Danio rerio). AJP-Cell Phys. 290: 371-378.
    16. PDF Hepler PK, M Bosch, L Cardenas, A Lovy-Wheeler, ST McKenna, KL Wilsen and JG Kunkel. (2005). Oscillatory pollen tube growth: imaging the underlying structures and physiological processes. Microscopy and Microanalysis 11 (Suppl 2), 148-149.
    17. PDF Zahiri R, A Sarafrazi, L Salehi and JG Kunkel. (2006) A geometric morphometric study on populations of Rice Stem Borer, Chilo suppressalis W. (Lep.: Crambidae) in northern Iran. Zoology in the Middle East 38: 73-84.
    18. PDF Hepler PK, A Lovy-Wheeler, ST McKenna and JG Kunkel. (2006). Ions and Pollen Tube Growth. In The Pollen Tube ed. by R. Malho. Plant Cell Monogr (3), Springer-Verlag Berlin Heidelberg, pp 43-69.
    19. PDF Lovy-Wheeler A, JG Kunkel, EG Allwood, PJ Hussey and PK Hepler. (2006). Oscillatory Increases in Alkalinity Anticipate Growth and May Regulate Actin Dynamics in Pollen Tubes of Lily. The Plant Cell 18: 2182-2193.
    20. PDF Cardenas L, ST McKenna, JG Kunkel and PK Hepler. (2006). NAD(P)H Oscillates in Pollen Tubes and Is Correlated with Tip Growth. Plant Phys. 142: 1-9.
    21. PDF Wilsen KL, A Lovy-Wheeler, B Voigt, D Menzel, JG Kunkel, PK Hepler. (2006). Imaging the actin cytoskeleton in growing pollen tubes. Sexual Plant Reproduction 19: 51-62.
    22. Text PaumGarten, N. (2007) Talk of the Town: Pest Dept.- Roach! The New Yorker (Jan 15).
    23. PDF Lucey S, F Juanes and JG Kunkel. (2007) Thermostability of Pleuronectid yolk protein, lipovitellin. Abstracts, American Fisheries Society Meeting, San Francisco, Sept 2-7, 2007.
    24. PDF Lovy-Wheeler A, Cárdenas L, Kunkel JG, Hepler PK (2007) Differential organelle movement on the actin cytoskeleton in lily pollen tubes. Cell Motil Cytoskeleton 64:217-232
    25. PDF Cardenas L, A Lovy-Wheeler, JG Kunkel and PK Hepler (2008) Pollen Tube Growth Oscillations and Intracellular Calcium Levels Are Reversibly Modulated by Actin Polymerization. Plant Physiol. 146: 1611-1621.
    26. PDF McKenna ST, JG Kunkel, M Bosch, CM Rounds, L Vidali, LJ Winship and PK Hepler (2009) Exocytosis Precedes and Predicts the Increase in Growth in Oscillating Pollen Tubes. Plant Cell 21: 1-15.


    1. PDF. Bowdan E and JG Kunkel. (1990). Patterns of ionic currents around the developing oocyte of the cockroach, Blattella germanica. Dev. Biol. 137: 266-275.
    2. PDF. Kunkel JG. (1990). Review of "OOCYTE GROWTH AND MATURATION". Edited by T A. Dettlaff and S. G. Vassetzky translation. Q Rev Biol 76: 506.
    3. Abstract Kindle H, B Lanzrein, JG Kunkel. (1990). The effect of ions, ion channel blockers, and ionophores on uptake of vitellogenin into cockroach follicles. Dev Biol 142: 386-91.
    4. PDF Karpells ST, DE Leonard and JG Kunkel. (1990). Cyclic fluctuations in arylphorin, the principal serum storage protein of Lymantria dispar, indicate multiple roles in development. Insect Biochem. 20: 73-82.
    5. PDF Telfer WH and JG Kunkel. (1991). THE FUNCTION AND EVOLUTION OF INSECT STORAGE HEXAMERS. Ann Rev Entomol 36: 205-28.
    6. PDF Kunkel JG. (1991). Models of pattern formation in insect oocytes. In Vivo 5: 443-456.
    7. PDF Zhang Y and JG Kunkel. (1992). Program of F-actin in the follicular epithelium during oogenesis of the German cockroach, Blattella germanica. Tiss. Cell 24:905-917.
    8. PDF Anderson M, E Bowdan and JG Kunkel. (1994). Comparison of defolliculated oocytes and intact follicles of the cockroach using the vibrating probe to record steady currents. Dev Biol 162: 111-22.
    9. PDF Zhang Y and JG Kunkel. (1994). Most egg calmodulin is a follicle cell contribution to the cytoplasm of the Blattella germanica oocyte. Dev Biol 161: 513-21.
    10. PDF Kunkel JG and PJS Smith (1994). Three-dimensional calibration of the non-invasive ion probe, NVP(i), of steady ionic currents. Biol. Bull. 187:271-2.
    11. PDF Keefe D, J Pepperell, P Rinaudo, J Kunkel and P Smith. (1995). Identification of Calcium Flux in Single Preimplantation Mouse Embryos with the Calcium-Sensitive Vibrating Probe. Biol. Bull. 189: 200.
    12. PDF Kunkel JG and EH Faszewski. (1995). Pattern of potassium ion and proton currents in the ovariole of the cockroach, Periplaneta americana, indicate future embryonic polarity. Biol. Bull. 189: 197-198.
    13. PDF Iyengar AR and JG Kunkel. (1995). Follicle cell calmodulin in Blattella germanica: Transcript accumulation during vitellogenesis is regulated by juvenile hormone. Dev Biol 170: 314-320.
    14. PDF Diss AL, JG Kunkel, ME Montgomery and DE Leonard. (1996). Effects of maternal nutrition and egg provisioning on parameters of larval hatch, survival and dispersal in the gypsy moth, Lymantria dispar L. Oecologia 106(4): 470-477.
    15. PDF Hartling RC, JJ Pereira and JG Kunkel. (1997). Characterization of a heat-stable fraction of lipovitellin and development of an immunoassay for vitellogenin and yolk protein in winter flounder (Pleuronectes americanus). J Exp Zool 278, 156-66.
    16. PDF Hartling RC and JG Kunkel. (1999). Developmental fate of the yolk protein lipovitellin in embryos and larvae of winter flounder, Pleuronectes americanus. J Exp Zool 284, 686-95.
    17. PDF Holdaway-Clark T, Feijo JA, GR Hackett, JG Kunkel and PK Hepler. (1997). Pollen Tube Growt h and the lntracellular Cytosolic Calcium Gradient Oscillate in Phase while Extracellular Calcium Influx Is Delayed. The Plant Cell 9: 1999-2010.
    18. PDF Feijo JA, J Sainhas, GR Hackett, JG Kunkel and PK Hepler. (1999). Growing pollen tubes possess a constitutive alkaline band in the clear zone and a growth-dependent acidic tip. J Cell Biol 144, 483-96.
    19. PDF Cardenas L, JA Feijo, JG Kunkel, F Sanchez, TL Holdaway-Clarke, PK Hepler and C Quinto. (1999) Rhizobium Nod factors induce increases in intracellular free calcium and extracellular calcium influxes in bean root hairs. The Plant Journal 19, 347-352.
    20. PDF Roy SJ, TL Holdaway-Clarke, GR Hackett, JG Kunkel, EM Lord and PK Hepler. (1999) Uncoupling secretion and tip growth in lily pollen tubes: evidence for the role of calcium in exocytosis. Plant J. 19:379-86.


    1. PDF Kunkel JG, LM Cherry, SM Case and AC Wilson. (1980). M-Statistics and Morphometric Divergence. Science 208, 1060-1061.
    2. Kunkel JG, GL Shepard, RA McCarthy, DB Ethier and JH Nordin. (1980). Concanavalin A reactivity and carbohydrate structure of Blattella germanica vitellin. Insect Biochem. 10: 703-714.
    3. PDF Kunkel JG. (1981) Cockroach Regeneration. Chapter 16 in THE AMERICAN COCKROACH, eds. WJ Bell and KG Adiyodi, Chapman and Hall, London, pp427-443.
    4. PDF Kunkel JG. (1981) A Minimal Model of Metamorphosis: Fat Body Competence to Respond to Juvenile Hormone. In Current Topics in Insect Endocrinology and Nutrition (G. Bhaskaran, S. Friedman and J.G. Rodriguez Eds.), pp 107-129. Plenum Pub.
    5. PDF Cherry LM, SM Case, JG Kunkel, JS Wyles, AC Wilson. 1982. Body Shape Metrics and Organismal Evolution. Evolution 36(5):914-933.
    6. PDF Wyles J, JG Kunkel and AC Wilson (1983). Birds, behavior, and anatomical evolution. PNAS 80: 4394-4397.
    7. PDF Duhamel RC and JG Kunkel (1983). Cockroach Larval-specific Protein, a Tyrosine-rich Serum Protein. J. Biol. Chem. 258: 14461-14465.
    8. Nordin JH, Gochoco CH, Wojchowski DM, Kunkel JG. (1984). A comparative study of the size-heterogeneous high mannose oligosaccharides of some insect vitellins. Comp Biochem Physiol B. 79(3):379-90. Abstract
    9. PDF Wilson AC, JG Kunkel and JS Wyles (1984). Morphological distance: an encounter between two perspectives in evolutionary biology. Evolution. 38: 1156-1159.
    11. PDF Storella JR, DM Wojchowski and JG Kunkel. 1985. Structure and embryonic degradation of two native vitellins in the cockroach, Periplaneta americana. Insect Biochem. 15: 259-275.
    12. Kunkel JG. 1986. Dorsoventral currents are associated with vitellogenesis in cockroach ovarioles. in IONIC CURRENTS IN DEVELOPMENT, R. Nuccitelli ed. Prog. Clin. Biol. Rsrch. 210: 165-17.
    13. Meeting Abstract PDF Kunkel JG, ES Bowdan, Y Zhang, H Kindle and B Lanzrein. (1986). Calcium antagonists inhibit cockroach oocyte and vitellogenic uptake. Amer. Zool. 26: 91A.
    14. PDF Kunkel JG and JH Nordin. (1986). Yolk proteins. In Comprehensive Insect Physiology Biochemistry Pharmacology (GA Kerkut and LI Gilbert, Eds.), Vol. 1, pp. 83-111. Pergamon Press, London.
    15. PDF Wojchowskii DM, P Parsons, JH Nordin, JG Kunkel. (1986). Processing of pro-vitellogenin in insect fat body: A role for high-mannose oligosaccharide. Dev. Biol. 116(2): 422-430. ISSN 0012-1606, ABS (ABS 2) ABS 3
    16. PDF Duhamel RC and JG Kunkel. (1987). Moulting-cycle regulation of haemolymph protein clearance in cockroaches: Possible size-dependent mechanism. J Insect Physiol 33: 155-158.
    17. PDF Kunkel JG. (1987). Analytical immunological techniques. In IMMUNOLOGICAL TECHNIQUES: ARTHROPODS (LI Gilbert and TA Miller, Eds.), pp. 1-41. Springer Verlag.
    18. Meeting Abs PDF Kunkel JG and E Bowdan. (1989). Modeling Currents About Panoistic Insect Oocytes. Am. Zool. 28: 98A.
    19. PDF Leonard D and Kunkel JG. (1989). NUTRITIONAL ECOLOGY: LYMANTRIA DISPAR AS A MODEL SYSTEM FOR STUDY OF SERUM STORAGE PROTEINS. In W. E. Wallner (ed.), Proc. Symp. New and Old World Tussock Moths. New Haven, CT. pp. 367-380.
    20. PDF Kunkel JG and E Bowdan. (1989). Modeling Currents About Vitellogenic Oocytes of the Cockroach, Blattella germanica. Biol Bull 176S: 96-102.


    1. Abstract Kunkel JG. (1973). Gonadotrophic effect of juvenile hormone in Blattella germanica: A rapid, simple quantitative bioassay. J. Insect Physiol. 19:1285-1297.
    2. PDF Kunkel JG. (1975) Cockroach Molting. I. Temporal organization of events during molting cycle Blattella germanica (L.). Biol. Bull., 148: 259-273.
    3. PDF Kunkel JG. (1975) Larval-Specific Protein in the Order Dictyoptera--II: Antagonistic Effects of Ecdysone and Regeneration on LSP Concentration in the hemolymph of the Oriental Cockroach, Blatta orientalis. Comp. Biochem. Physiol. 51B: 177 to 180.
    4. PDF Kunkel JG and ML Pan. (1976). Selectivity of yolk protein uptake: Comparison of vitellogenins of two insects. J. Insect Physiol. 22: 809-818.
    5. PDF Kunkel JG. (1977) Cockroach Molting. II. The Nature of Regeneration-Induced Delay of Molting Hormone Secretion. Biol. Bull., 153: 145-162.
    6. PDF Duhamel RC and JG Kunkel. (1978). A molting rhythm for serum proteins of the cockroach, Blatta orientalis. Comp Biochem Physiol 60B: 333-337.
    7. PDF Greenberg SLW, JG Kunkel and AM Stuart (1978) Vitellogenesis in a primitive termite, Zootermopsis angusticollis (Hagen) (Hodotermitidae). Biol. Bull. 155: 336-346.
    8. Storella J. R. and Kunkel J. G. (1979) Processing and utilization of vitellin in the cockroach egg. Am. Zool. 19, 146.
    9. PDF Hagedorn HH, and JG Kunkel (1979). Vitellogenin and Vitellin in Insects. Ann Rev Entomol 24, 475-505.
    10. PDF | HTML Cherry LM, SM Case, JG Kunkel and AC Wilson. (1979). Comparisons of frogs, humans, and chimpanzees. Science 204, 435.


    1. HTML Kunkel JG. (1966). Development and the availability of food in the German cockroach, Blattella germanica (L.). J. Insect Physiol. 12, 227-235.

    Revised 7/05/2017 by JGK