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McCormick Laboratory
Environmental Physiology of Fish

University of Massachusetts, Amherst

Curriculum Vitae: Amy M. Regish

Amy Regish

Research Physiologist

2001: M.S. University of Massachusetts, Amherst (Aquatic Toxicology)
1988: B.S. University of Vermont, Burlington (Animal Sciences)

Research Interests:

I am broadly interested in the physiologic response of anadromous fish species to natural and anthropogenic alterations of aquatic ecosystems. Some of the many challenges faced by anadromous fish species are from warming temperatures due to climate change, manmade impediments to migration, and contaminant exposure. The impact of these perturbations on thermal tolerance, stress physiology, and osmoregulation is of particular concern in the conservation and restoration efforts directed towards anadromous fish species in the Northeast. Research to help develop an understanding the physiological responses will help in these efforts.


Kelly, J. T., Lerner, D. T., O'Dea, M. F., Regish, A. M., Monette, M. Y., Hawkes, J. P., Nislow, K. H. and McCormick, S. D. (2015), Evidence for episodic acidification effects on migrating Atlantic salmon Salmo salar smolts. J Fish Biol, 87: 1129–1146. doi:10.1111/jfb.12763

Mccormick, S. D., Haro, A., Lerner, D. T., O’Dea, M. F., and Regish, A. M. (2014). Migratory patterns of hatchery and stream-reared Atlantic salmon Salmo salar smolts in the Connecticut River, U.S.A. Journal of Fish Biology.

McCormick, S.D., Regish, A.M. and Christensen, A.K. 2009. Distinct freshwater and seawater isoforms of Na+/K+-ATPase in gill chloride cells of Atlantic salmon. Journal of Experimental Biology 212: 3994-4001.

McCormick, S.D., Regish, A.M., O'Dea, M.F. and Shrimpton, J.M. 2008. Are we missing a mineralocorticoid in teleost fish? Effects of cortisol, deoxycorticosterone and aldosterone on osmoregulation, gill Na+/K+-ATPase activity and isoform mRNA levels in Atlantic salmon. General and Comparative Endocrinology 157: 35-40.

McCormick, S.D., O'Dea, M.F., Moeckel, A.M., Lerner, D.T. and Björnsson, B.Th. 2005. Endocrine disruption of parr-smolt transformation and seawater tolerance of Atlantic salmon by 4-nonylphenol and 17β-estradiol. General and Comparative Endocrinology 142: 280-288

McCormick, S.D., O'Dea, M.F., Moeckel, A.M., Björnsson, B.Th. 2003. Endocrine and physiological changes in Atlantic salmon smolts following hatchery release. Aquaculture 222: 45-57

Campbell, J.S., Seger, R., Jensen, A.M., and Krebs, E.G. The Map Kinase Cascade. Recent Progress in Hormone Research. Vol. 50, pp. 131-159, 1995.

Ahn, N.G., Campbell, J.S., Seger, R., Jensen, A.M., Graves, L.M., and Krebs, E.G.. Metabolic Labeling of Mitogen Activated Protein Kinase Kinase in A431 Cells Demonstrates Phosphorylation on Serine and Threonine Residues.  Proc. Natl. Acad. Sci. Vol. 90, pp. 5143-5147, June 1993.

Seger, R., Ahn, N.G., Posada, J., Munar, E.S.,Jensen, A.M.,Cooper, J.,Cobb, M.H., and Krebs, E.G..  Purification and Characterization of Mitogen Activated Protein Kinase Activators from Epidermal Growth Factor Stimulated A431 Cells. The Journal of Biological Chemistry. Vol. 267(20), pp. 14373-14381, July 15, 1992.

Seger, R., Seger, D., Lozeman, F.J., Ahn, N.G., Graves, L.M., Campbell, J.S., Ericsson, L., Harrylock, M., Jensen, A.M., and Krebs, E.G. Human T-Cell Mitogen Activated Protein Kinase Kinases are Related to Yeast Signal Transduction Kinases. The Journal of Biological Chemistry. Vol. 267(36), pp. 25628-25631, Dec 25, 1992.

Farrington, G.K., Lynch, P.,Jensen, A., Bonhlein, E., Doten, V, Maione, T., Daly, T., and Rusche, J. The Lentivirus Regulatory Proteins REV and REX are Site Specific RNA Binding Proteins. Adv. Exp. Med. Biol. Vol. 303, pp. 15-22, 1991