fish gills showing chloride cells

McCormick Laboratory
Fish Physiology

University of Massachusetts, Amherst

Model of ion transport in seawater and freshwater chloride cells

Toggle between the seawater and freshwater model by clicking the SW or FW button.

Key to the components of the model:

Grey - Chloride cell
Purple - Accessory cell

SW - Seawater-type chloride cell
CFTR - Cystic Fibrosis Transmembrane Conductance Regulator
NKA - Na+,K+-ATPase [alpha1b subunit]
NKCC - Na+-K+-2Cl-Cotransporter
Kir - inward rectifier K+ channel

FW - Freshwater-type chloride cell
AE - Anion Exchanger
V-HA - V-type H+-ATPase
ENaC - Epithelial Na+ Channel
NHE - Na+,H+ Exchanger
NCC - Na+-2Cl-Cotransporter
NKA - Na+,K+-ATPase [alpha1a subunit]

This flash animation is the original work of . It is copyright and all rights are reserved. Permission is granted for not-for-profit educational use of this model, provided the author is appropriately credited.

Download animated PowerPoint slide*:[ CCell.ppt] (150 KB)
Download Flash file:[ CCell - Flash]

* Insert slide into presentation, run animation by toggeling buttons, return to presention by clicking on periphery of slide.
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