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McCormick Laboratory
Fish Physiology

University of Massachusetts, Amherst

Curriculum Vitae: Joseph G. Chadwick Jr.

Joseph G. Chadwick Jr.

Doctoral Student

Education
2005: B.A. Wheaton College

Research Interests
I am interested in the hormonal regulation of behavior, development, and osmoregulation in fishes. Due to their life histories, anadromous fishes face a range of osmotic challenges. The capacity to meet these osmotic challenges is determined to a great degree by the endocrine system. Recent work from our lab has shown that contaminants, including endocrine disrupters, can disturb development and osmoregulation in Atlantic Salmon. I am interested in the mechanisms of endocrine disruption and stress physiology in anadromous fishes. I hope that my work can be applied to the conservation and restoration of endangered anadromous fishes.

Publications
Molenda-Figueira, H.A, Murphy, S.D., Shea, K.L., Siegal, N.K., Zhao, Y., Chadwick, J.G., Denner, L.A. and Tetel, M.J. Steroid receptor coactivator-1 from brain physically interacts differentially with steroid receptor subtypes. Endocrinology, Rapid Electronic Publication first published on Jun 19, 2008 as DOI:10.1210/en.2008-0048 [pdf]

Abstracts:
Im, D., Yore, M.A., Chadwick, J.G., Tetel, M.J. Steroid receptor coactivator-2 (SRC-2) from rat brain interacts differently with estrogen receptor and progesterone receptor subtypes. The Endocrine Society, 2008.

Yore, M.A., Im, D., Chadwick, J.G., Tetel, M.J. Steroid receptor coactivator-2 (SRC-2) from female rat hypothalamus and hippocampus interacts differently with the progestin receptor isoforms. Society for Neuroscience, 2007.

Tetel, M.J., Molenda, H.A., Yore, M.A., Im, D., Chadwick, J.G., Steroid hormone action: From the test tube to the brain. International Congress of Neuroethology, Vancouver, Canada, 2007.

Tetel, M.J., Yore, M.A., Webb, L.K., Chadwick, J.G., Molenda-Figueira, H.A. Steroid receptor coactivator-2 is expressed in female rat brain and physically interacts with estrogen receptor (ER)α, but not ERß, in a ligand dependent manner. Society for Neuroscience, 258.9, 2006.

Brennessel, B., Chadwick, J., Stewart-Swift, C., Warren, N. The importance of the salt marsh as a nursery for Diamondback terrapins. The State of the Harbor Conference, Wellfleet, Massachusetts, 2003.

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