Curriculum Vitae: Joseph G. Chadwick Jr.
2005: B.A. Wheaton College
I am broadly interested in how global warming may affect cold-water fish species. In spite of the looming threat of global warming, the mechanisms by which temperature affects populations are largely unknown. In particular, I hope to determine the impact of acute and chronic thermal increases on the stress and growth responses in brook trout at the individual and population level. There is increased interest in utilizing mediators of the stress response as indicators of both individual and population level response to environmental stressors such as elevated temperatures. Additionally, elevated temperatures may influence hormonal control of growth via mediators of the stress response. Understanding the relationships between temperature, stress, and growth is essential to understanding the physiological responses to increased temperatures that may be common to many species. Additionally, I hope to describe specific biomarkers that will be useful in determining if brook trout populations have been exposed to stressful temperature increases.
Yore, M.A., Im, D., Webb, L.K., Zhao, Y., Chadwick Jr, J.G., Molenda-Figueira, H.A., Denner, L.A.,Tetel, M.J. Steroid receptor coactivator-2 expression in brain and physical associations with steroid receptors. Neuroscience, 169: 1017-1028, 2010.[pdf]
Cyr, N.E., Kua, L.H., Bruce, L.A., Chadwick Jr, J.G., Tetel, M.J. and Wolfson, A.J. Nuclear thimet oligopeptidase is coexpressed with oestrogen receptor α in the hypothalamus of female mice and regulated by oestradiol. Journal of Neuroendocrinology, 22: 936-943, 2010.
Molenda-Figueira, H.A., Murphy, S.D., Shea, K.L., Siegal, N.K., Zhao, Y., Chadwick Jr, J.G., Denner, L.A., Tetel, M.J. SRC-1 from brain physically associates differentially with steroid receptor subtypes. Endocrinology, 149: 5272-5279, 2008.[pdf]
Chadwick Jr, J.G., McCormick, S.D. Upper themal limits of growth in brook trout (Salvelinus fontinalis) and their relation to stress physiology. American Physiological Society: Global Change & Global Science: Comparative Physiology in a Changing World, 7.17, 2010.
Ackeifi, C., Tognoni, C.M., Chadwick, J.G., Tetel, M.J. Steroid receptor coactivator-1 (SRC-1) and SRC-2 are coexpressed with progestin receptors and regulated by estradiol in female mouse brain. Society for Neuroscience, 273.1, 2009.
Tognoni, C., Ackeifi, C., Chadwick, J.G., Tetel, M.J. Cells in Female Mouse Brain Coexpress Steroid Receptors and Nuclear Receptor Coactivators. Endocrine Society, P1-658, 2009.
Im, D., Yore, M.A., Chadwick, J.G., Tetel, M.J. Steroid receptor coactivator-2 (SRC-2) from rat brain interacts differently with estrogen receptor and progesterone receptor subtypes. The Endocrine Society, 2008.
Yore, M.A., Im, D., Chadwick, J.G., Tetel, M.J. Steroid receptor coactivator-2 (SRC-2) from female rat hypothalamus and hippocampus interacts differently with the progestin receptor isoforms. Society for Neuroscience, 2007.
Tetel, M.J., Molenda, H.A., Yore, M.A., Im, D., Chadwick, J.G., Steroid hormone action: From the test tube to the brain. International Congress of Neuroethology, Vancouver, Canada, 2007.
Tetel, M.J., Yore, M.A., Webb, L.K., Chadwick, J.G., Molenda-Figueira, H.A. Steroid receptor coactivator-2 is expressed in female rat brain and physically interacts with estrogen receptor (ER)α, but not ERß, in a ligand dependent manner. Society for Neuroscience, 258.9, 2006.
Brennessel, B., Chadwick, J., Stewart-Swift, C., Warren, N. The importance of the salt marsh as a nursery for Diamondback terrapins. The State of the Harbor Conference, Wellfleet, Massachusetts, 2003.